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What You’re Really Seeing Under a Microscope



Are we actually seeing viruses—or just artifacts of the microscope?

The question of whether we’re truly observing viral particles—or merely artifacts produced during sample preparation—remains controversial. When using electron microscopy, we’re not directly viewing carbon-based biological material. Instead, biological samples must be coated with a thin layer of conductive metal, such as gold or platinum, to become visible under the electron beam.

This raises important questions: Did the particles seen under the microscope exist in the living organism, or were they introduced or distorted during preparation? Are we observing authentic biological features—or artifacts?
The late Dr. Harold Hillman, a neurobiologist and critic of electron microscopy, argued that many of the structures identified under these microscopes may not represent biological reality at all, but rather, the consequences of aggressive sample processing.

As we interpret microscopic images—especially those claimed to show viruses—we must critically consider whether we’re viewing the natural state of biology, or the technological illusions of the tools we use.

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